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TP53 p.R337H prevalence in a series of Brazilian hereditary breast cancer families

BACKGROUND: Approximately 5-10% of breast cancers are hereditary. Among hereditary syndromes, Hereditary Breast and Ovarian Cancer Syndrome (HBOC) and Li-Fraumeni Syndrome (LFS) have received the most attention. HBOC is due to mutations in the BRCA1 and BRCA2 genes and is characterized by breast ade...

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Detalles Bibliográficos
Autores principales:	Cury, Nathalia M, Ferraz, Victor EF, Silva, Wilson A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995619/ https://www.ncbi.nlm.nih.gov/pubmed/24625245 http://dx.doi.org/10.1186/1897-4287-12-8

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