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The Effect of Antifibrotic Drugs in Rat Precision-Cut Fibrotic Liver Slices
Two important signaling pathways in liver fibrosis are the PDGF- and TGFβ pathway and compounds inhibiting these pathways are currently developed as antifibrotic drugs. Testing antifibrotic drugs requires large numbers of animal experiments with high discomfort. Therefore, a method to study these dr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995767/ https://www.ncbi.nlm.nih.gov/pubmed/24755660 http://dx.doi.org/10.1371/journal.pone.0095462 |