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Sunitinib in combination with trastuzumab for the treatment of advanced breast cancer: activity and safety results from a phase II study
BACKGROUND: This phase II study evaluated the efficacy and safety/tolerability of sunitinib plus trastuzumab in patients with HER2-positive advanced breast cancer (ABC). METHODS: Eligible patients received sunitinib 37.5 mg/day and trastuzumab administered either weekly (loading, 4 mg/kg; then weekl...
Autores principales: | Bachelot, Thomas, Garcia-Saenz, Jose A, Verma, Sunil, Gutierrez, Maya, Pivot, Xavier, Kozloff, Mark F, Prady, Catherine, Huang, Xin, Khosravan, Reza, Wang, Zhixiao, Cesari, Rossano, Tassell, Vanessa, Kern, Kenneth A, Blay, Jean-Yves, Lluch, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995914/ https://www.ncbi.nlm.nih.gov/pubmed/24606768 http://dx.doi.org/10.1186/1471-2407-14-166 |
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