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Self-Administration of Ethanol, Cocaine, or Nicotine Does Not Decrease the Soma Size of Ventral Tegmental Area Dopamine Neurons

Our previous observations show that chronic opiate administration, including self-administration, decrease the soma size of dopamine (DA) neurons in the ventral tegmental area (VTA) of rodents and humans, a morphological change correlated with increased firing rate and reward tolerance. Given that a...

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Detalles Bibliográficos
Autores principales: Mazei-Robison, Michelle S., Appasani, Raghu, Edwards, Scott, Wee, Sunmee, Taylor, Seth R., Picciotto, Marina R., Koob, George F., Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995955/
https://www.ncbi.nlm.nih.gov/pubmed/24755634
http://dx.doi.org/10.1371/journal.pone.0095962