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Enhanced Antitumor Efficacy of an Oncolytic Herpes Simplex Virus Expressing an Endostatin–Angiostatin Fusion Gene in Human Glioblastoma Stem Cell Xenografts

Viruses have demonstrated strong potential for the therapeutic targeting of glioblastoma stem cells (GSCs). In this study, the use of a herpes simplex virus carrying endostatin–angiostatin (VAE) as a novel therapeutic targeting strategy for glioblastoma-derived cancer stem cells was investigated. We...

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Detalles Bibliográficos
Autores principales:	Zhang, Guobin, Jin, Guishan, Nie, Xiutao, Mi, Ruifang, Zhu, Guidong, Jia, William, Liu, Fusheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995956/ https://www.ncbi.nlm.nih.gov/pubmed/24755877 http://dx.doi.org/10.1371/journal.pone.0095872

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