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Secondary Structure Changes in ApoA-I Milano (R173C) Are Not Accompanied by a Decrease in Protein Stability or Solubility

Apolipoprotein A-I (apoA-I) is the main protein of high-density lipoprotein (HDL) and a principal mediator of the reverse cholesterol transfer pathway. Variants of apoA-I have been shown to be associated with hereditary amyloidosis. We previously characterized the G26R and L178H variants that both p...

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Detalles Bibliográficos
Autores principales:	Petrlova, Jitka, Dalla-Riva, Jonathan, Mörgelin, Matthias, Lindahl, Maria, Krupinska, Ewa, Stenkula, Karin G., Voss, John C., Lagerstedt, Jens O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995965/ https://www.ncbi.nlm.nih.gov/pubmed/24755625 http://dx.doi.org/10.1371/journal.pone.0096150

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