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The Mucosal Adjuvant Cyclic di-AMP Exerts Immune Stimulatory Effects on Dendritic Cells and Macrophages

The cyclic di-nucleotide bis-(3′,5′)-cyclic dimeric adenosine monophosphate (c-di-AMP) is a candidate mucosal adjuvant with proven efficacy in preclinical models. It was shown to promote specific humoral and cellular immune responses following mucosal administration. To date, there is only fragmenta...

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Detalles Bibliográficos
Autores principales: Škrnjug, Ivana, Rueckert, Christine, Libanova, Rimma, Lienenklaus, Stefan, Weiss, Siegfried, Guzmán, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996008/
https://www.ncbi.nlm.nih.gov/pubmed/24755640
http://dx.doi.org/10.1371/journal.pone.0095728