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The Mucosal Adjuvant Cyclic di-AMP Exerts Immune Stimulatory Effects on Dendritic Cells and Macrophages
The cyclic di-nucleotide bis-(3′,5′)-cyclic dimeric adenosine monophosphate (c-di-AMP) is a candidate mucosal adjuvant with proven efficacy in preclinical models. It was shown to promote specific humoral and cellular immune responses following mucosal administration. To date, there is only fragmenta...
Autores principales: | Škrnjug, Ivana, Rueckert, Christine, Libanova, Rimma, Lienenklaus, Stefan, Weiss, Siegfried, Guzmán, Carlos A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996008/ https://www.ncbi.nlm.nih.gov/pubmed/24755640 http://dx.doi.org/10.1371/journal.pone.0095728 |
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