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Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes

BACKGROUND: Lysophosphatidic acid (LPA) is a bioactive phospholipid with a potentially causative role in neurotrauma. Blocking LPA signaling with the LPA-directed monoclonal antibody B3/Lpathomab is neuroprotective in the mouse spinal cord following injury. FINDINGS: Here we investigated the use of...

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Detalles Bibliográficos
Autores principales:	Crack, Peter J, Zhang, Moses, Morganti-Kossmann, Maria Cristina, Morris, Andrew J, Wojciak, Jonathan M, Fleming, Jonathan K, Karve, Ila, Wright, David, Sashindranath, Maithili, Goldshmit, Yona, Conquest, Alison, Daglas, Maria, Johnston, Leigh A, Medcalf, Robert L, Sabbadini, Roger A, Pébay, Alice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996049/ https://www.ncbi.nlm.nih.gov/pubmed/24576351 http://dx.doi.org/10.1186/1742-2094-11-37

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