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Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles

BACKGROUND: Diesel exhaust is associated with cardiovascular and respiratory mortality and morbidity. Acute exposure leads to increased IL-8 expression and airway neutrophilia, however the mechanism of this response is unknown. Objectives: As cigarette smoke-induced IL-8 expression by epithelial cel...

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Detalles Bibliográficos
Autores principales: Parnia, Sam, Hamilton, Lynnsey M, Puddicombe, Sarah M, Holgate, Stephen T, Frew, Anthony J, Davies, Donna E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996104/
https://www.ncbi.nlm.nih.gov/pubmed/24555532
http://dx.doi.org/10.1186/1465-9921-15-22

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