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Doing without codeine: why and what are the alternatives?
Codeine is a mild opioid widely used as an analgesic in various age groups, including various pediatric settings. It is a prodrug that owes its analgesic effect almost entirely to the principal metabolite: morphine. The genetic polymorphisms can contribute to making the pharmacokinetics of codeine h...
Autores principales: | Benini, Franca, Barbi, Egidio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996141/ https://www.ncbi.nlm.nih.gov/pubmed/24517264 http://dx.doi.org/10.1186/1824-7288-40-16 |
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