Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury

BACKGROUND: Axon degeneration is a characteristic feature of multiple neuropathologic states and is also a mechanism of physiological neurodevelopmental pruning. The vast majority of in vivo studies looking at axon degeneration have relied on the use of classical silver degeneration stains, which ha...

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Detalles Bibliográficos
Autores principales: Sokolowski, Jennifer D, Gamage, Kanchana K, Heffron, Daniel S, LeBlanc, Andrea C, Deppmann, Christopher D, Mandell, James W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996144/
https://www.ncbi.nlm.nih.gov/pubmed/24507707
http://dx.doi.org/10.1186/2051-5960-2-16

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