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Epigenetic reprogramming, gene expression and in vitro development of porcine SCNT embryos are significantly improved by a histone deacetylase inhibitor—m-carboxycinnamic acid bishydroxamide (CBHA)

Insufficient epigenetic reprogramming of donor nuclei is believed to be one of the most important causes of low development efficiency of mammalian somatic cell nuclear transfer (SCNT). Previous studies have shown that both the in vitro and in vivo development of mouse SCNT embryos could be increase...

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Detalles Bibliográficos
Autores principales: Song, Yuran, Hai, Tang, Wang, Ying, Guo, Runfa, Li, Wei, Wang, Liu, Zhou, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996156/
https://www.ncbi.nlm.nih.gov/pubmed/24627095
http://dx.doi.org/10.1007/s13238-014-0034-3