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Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients

Flagellated protozoa that cause bronchopulmonary symptoms in humans are commonly neglected. These protozoal forms which were presumed to be “flagellated protozoa” have been previously identified in immunosuppressed patients in a number of studies, but have not been certainly classified so far. Since...

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Autores principales: Kilimcioglu, Ali Ahmet, Havlucu, Yavuz, Girginkardesler, Nogay, Çelik, Pınar, Yereli, Kor, Özbilgin, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996290/
https://www.ncbi.nlm.nih.gov/pubmed/24804259
http://dx.doi.org/10.1155/2014/912346
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author Kilimcioglu, Ali Ahmet
Havlucu, Yavuz
Girginkardesler, Nogay
Çelik, Pınar
Yereli, Kor
Özbilgin, Ahmet
author_facet Kilimcioglu, Ali Ahmet
Havlucu, Yavuz
Girginkardesler, Nogay
Çelik, Pınar
Yereli, Kor
Özbilgin, Ahmet
author_sort Kilimcioglu, Ali Ahmet
collection PubMed
description Flagellated protozoa that cause bronchopulmonary symptoms in humans are commonly neglected. These protozoal forms which were presumed to be “flagellated protozoa” have been previously identified in immunosuppressed patients in a number of studies, but have not been certainly classified so far. Since no human cases of bronchopulmonary flagellated protozoa were reported from Turkey, we aimed to investigate these putative protozoa in immunosuppressed patients who are particularly at risk of infectious diseases. Bronchoalveolar lavage fluid samples of 110 immunosuppressed adult patients who were admitted to the Department of Chest Diseases, Hafsa Sultan Hospital of Celal Bayar University, Manisa, Turkey, were examined in terms of parasites by light microscopy. Flagellated protozoal forms were detected in nine (8.2%) of 110 cases. Metronidazole (500 mg b.i.d. for 30 days) was given to all positive cases and a second bronchoscopy was performed at the end of the treatment, which revealed no parasites. In conclusion, immunosuppressed patients with bronchopulmonary symptoms should attentively be examined with regard to flagellated protozoa which can easily be misidentified as epithelial cells.
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spelling pubmed-39962902014-05-06 Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients Kilimcioglu, Ali Ahmet Havlucu, Yavuz Girginkardesler, Nogay Çelik, Pınar Yereli, Kor Özbilgin, Ahmet Biomed Res Int Research Article Flagellated protozoa that cause bronchopulmonary symptoms in humans are commonly neglected. These protozoal forms which were presumed to be “flagellated protozoa” have been previously identified in immunosuppressed patients in a number of studies, but have not been certainly classified so far. Since no human cases of bronchopulmonary flagellated protozoa were reported from Turkey, we aimed to investigate these putative protozoa in immunosuppressed patients who are particularly at risk of infectious diseases. Bronchoalveolar lavage fluid samples of 110 immunosuppressed adult patients who were admitted to the Department of Chest Diseases, Hafsa Sultan Hospital of Celal Bayar University, Manisa, Turkey, were examined in terms of parasites by light microscopy. Flagellated protozoal forms were detected in nine (8.2%) of 110 cases. Metronidazole (500 mg b.i.d. for 30 days) was given to all positive cases and a second bronchoscopy was performed at the end of the treatment, which revealed no parasites. In conclusion, immunosuppressed patients with bronchopulmonary symptoms should attentively be examined with regard to flagellated protozoa which can easily be misidentified as epithelial cells. Hindawi Publishing Corporation 2014 2014-04-03 /pmc/articles/PMC3996290/ /pubmed/24804259 http://dx.doi.org/10.1155/2014/912346 Text en Copyright © 2014 Ali Ahmet Kilimcioglu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kilimcioglu, Ali Ahmet
Havlucu, Yavuz
Girginkardesler, Nogay
Çelik, Pınar
Yereli, Kor
Özbilgin, Ahmet
Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_full Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_fullStr Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_full_unstemmed Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_short Putative Bronchopulmonary Flagellated Protozoa in Immunosuppressed Patients
title_sort putative bronchopulmonary flagellated protozoa in immunosuppressed patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996290/
https://www.ncbi.nlm.nih.gov/pubmed/24804259
http://dx.doi.org/10.1155/2014/912346
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