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In vivo therapeutic potential of Dicer-hunting siRNAs targeting infectious hepatitis C virus.

The development of RNA interference (RNAi)-based therapy faces two major obstacles: selecting small interfering RNA (siRNA) sequences with strong activity, and identifying a carrier that allows efficient delivery to target organs. Additionally, conservative region at nucleotide level must be targete...

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Detalles Bibliográficos
Autores principales:	Watanabe, Tsunamasa, Hatakeyama, Hiroto, Matsuda-Yasui, Chiho, Sato, Yusuke, Sudoh, Masayuki, Takagi, Asako, Hirata, Yuichi, Ohtsuki, Takahiro, Arai, Masaaki, Inoue, Kazuaki, Harashima, Hideyoshi, Kohara, Michinori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996463/ https://www.ncbi.nlm.nih.gov/pubmed/24756133 http://dx.doi.org/10.1038/srep04750

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