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Fpk1/2 kinases regulate cellular sphingoid long-chain base abundance and alter cellular resistance to LCB elevation or depletion

Sphingolipids are a family of eukaryotic lipids biosynthesized from sphingoid long-chain bases (LCBs). Sphingolipids are an essential class of lipids, as their depletion results in cell death. However, acute LCB supplementation is also toxic; thus, proper cellular LCB levels should be maintained. To...

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Detalles Bibliográficos
Autores principales:	Yamane-Sando, Yukari, Shimobayashi, Etsuko, Shimobayashi, Mitsugu, Kozutsumi, Yasunori, Oka, Shogo, Takematsu, Hiromu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Ltd. 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996568/ https://www.ncbi.nlm.nih.gov/pubmed/24510621 http://dx.doi.org/10.1002/mbo3.160

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