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The balance between cell cycle arrest and cell proliferation: control by the extracellular matrix and by contact inhibition
To understand the dynamics of the cell cycle, we need to characterize the balance between cell cycle arrest and cell proliferation, which is often deregulated in cancers. We address this issue by means of a detailed computational model for the network of cyclin-dependent kinases (Cdks) driving the m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996587/ https://www.ncbi.nlm.nih.gov/pubmed/24904738 http://dx.doi.org/10.1098/rsfs.2013.0075 |