Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers

Epigenetic therapy is emerging as a potential therapy for solid tumors. To investigate its mechanism of action, we performed integrative expression and methylation analysis of 63 cancer cell lines (breast, colorectal, and ovarian) after treatment with the DNA methyltransferase inhibitor 5-azacitidin...

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Detalles Bibliográficos
Autores principales: Li, Huili, Chiappinelli, Katherine B., Guzzetta, Angela A., Easwaran, Hariharan, Yen, Ray-Whay Chiu, Vatapalli, Rajita, Topper, Michael J., Luo, Jianjun, Connolly, Roisin M., Azad, Nilofer S., Stearns, Vered, Pardoll, Drew M., Davidson, Nancy, Jones, Peter A., Slamon, Dennis J., Baylin, Stephen B., Zahnow, Cynthia A., Ahuja, Nita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996658/
https://www.ncbi.nlm.nih.gov/pubmed/24583822

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