A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity

C-X-C chemokine receptor type 4 (CXCR4) is known to regulate lung, pancreatic and prostate cancer stem cells. In breast cancer, CXCR4 signalling has been reported to be a mediator of metastasis, and is linked to poor prognosis. However its role in normal and malignant breast stem cell function has n...

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Detalles Bibliográficos
Autores principales: Ablett, Matthew P., O'Brien, Ciara S., Sims, Andrew H., Farnie, Gillian, Clarke, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996659/
https://www.ncbi.nlm.nih.gov/pubmed/24583601

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