Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells

Cheliensisine A (Chel A) as a novel styryl-lactone isolated from Goniothalamus cheliensis Hu has been indicated to be a chemotherapeutic agent in Leukemia HL-60 cells. However, its potential for cancer treatment and the underlying mechanisms are not deeply investigated to the best of our knowledge....

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Detalles Bibliográficos
Autores principales: Zhang, Jingjie, Gao, Guangxun, Chen, Liang, Li, Jingxia, Deng, Xu, Zhao, Qin-shi, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996661/
https://www.ncbi.nlm.nih.gov/pubmed/24553354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996661/
https://www.ncbi.nlm.nih.gov/pubmed/24553354

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