Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

Multiple myeloma (MM) is a B cell malignancy characterized by clonal proliferation of plasma cells in the bone marrow. With the advent of novel targeted agents, the median survival rate has increased to 5−7 years. However, majority of patients with myeloma suffer relapse or develop chemoresistance t...

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Detalles Bibliográficos
Autores principales: Siveen, Kodappully Sivaraman, Mustafa, Nurulhuda, Li, Feng, Kannaiyan, Radhamani, Ahn, Kwang Seok, Kumar, Alan Prem, Chng, Wee-Joo, Sethi1, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996662/
https://www.ncbi.nlm.nih.gov/pubmed/24504138

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