Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma

Mantle cell lymphoma (MCL) is considered one of the most challenging lymphoma, with limited responses to current therapies. Acadesine, a nucleoside analogue has shown antitumoral effects in different preclinical cancer models as well as in a recent phase I/II clinical trial conducted in patients wit...

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Detalles Bibliográficos
Autores principales: Montraveta, Arnau, Xargay-Torrent, Sílvia, López-Guerra, Mónica, Rosich, Laia, Pérez-Galán, Patricia, Salaverria, Itziar, Beà, Silvia, Kalko, Susana G., de Frias, Mercè, Campàs, Clara, Roué, Gaël, Colomer, Dolors
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996675/
https://www.ncbi.nlm.nih.gov/pubmed/24519895

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