Cargando…

Rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging

Trilateral retinoblastoma (TRb) is a rare syndrome associating hereditary bilateral or unilateral retinoblastoma (Rb) with an intracranial neuroblastic tumor. The latter arises in the midline, most often in the pineal gland, less frequently in the suprasellar or parasellar region. The outcome is usu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamaleshwaran, Koramadai Karuppusamy, Shibu, Deepu K, Mohanan, Vyshakh, Shinto, Ajit Sugunan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996766/
https://www.ncbi.nlm.nih.gov/pubmed/24761068
http://dx.doi.org/10.4103/0972-3919.130303
_version_ 1782313092540006400
author Kamaleshwaran, Koramadai Karuppusamy
Shibu, Deepu K
Mohanan, Vyshakh
Shinto, Ajit Sugunan
author_facet Kamaleshwaran, Koramadai Karuppusamy
Shibu, Deepu K
Mohanan, Vyshakh
Shinto, Ajit Sugunan
author_sort Kamaleshwaran, Koramadai Karuppusamy
collection PubMed
description Trilateral retinoblastoma (TRb) is a rare syndrome associating hereditary bilateral or unilateral retinoblastoma (Rb) with an intracranial neuroblastic tumor. The latter arises in the midline, most often in the pineal gland, less frequently in the suprasellar or parasellar region. The outcome is usually fatal because of secondary spinal dissemination. We report 10-year-old boy presented with a right eye proptosis and leukocoria, and the magnetic resonance imaging (MRI) showed right orbital mass lesion infiltrating optic nerve and diagnosis of retinoblastoma was made. He was referred for fluorodeoxyglucose-positron emission tomography/computed tomography (FDG PET/CT) to find out the extent of the disease. PET/CT showed abnormal FDG-uptake within right orbital mass lesion, suprasellar enhancing lesion and drop metastasis in the cervical spinal canal level. He was diagnosed as a case of TRb with spinal canal drop metastasis. He underwent chemotherapy and craniospinal irradiation.
format Online
Article
Text
id pubmed-3996766
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-39967662014-04-23 Rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging Kamaleshwaran, Koramadai Karuppusamy Shibu, Deepu K Mohanan, Vyshakh Shinto, Ajit Sugunan Indian J Nucl Med Case Report Trilateral retinoblastoma (TRb) is a rare syndrome associating hereditary bilateral or unilateral retinoblastoma (Rb) with an intracranial neuroblastic tumor. The latter arises in the midline, most often in the pineal gland, less frequently in the suprasellar or parasellar region. The outcome is usually fatal because of secondary spinal dissemination. We report 10-year-old boy presented with a right eye proptosis and leukocoria, and the magnetic resonance imaging (MRI) showed right orbital mass lesion infiltrating optic nerve and diagnosis of retinoblastoma was made. He was referred for fluorodeoxyglucose-positron emission tomography/computed tomography (FDG PET/CT) to find out the extent of the disease. PET/CT showed abnormal FDG-uptake within right orbital mass lesion, suprasellar enhancing lesion and drop metastasis in the cervical spinal canal level. He was diagnosed as a case of TRb with spinal canal drop metastasis. He underwent chemotherapy and craniospinal irradiation. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3996766/ /pubmed/24761068 http://dx.doi.org/10.4103/0972-3919.130303 Text en Copyright: © Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kamaleshwaran, Koramadai Karuppusamy
Shibu, Deepu K
Mohanan, Vyshakh
Shinto, Ajit Sugunan
Rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging
title Rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging
title_full Rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging
title_fullStr Rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging
title_full_unstemmed Rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging
title_short Rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging
title_sort rare case of trilateral retinoblastoma with spinal canal drop metastasis detected with fluorine-18 fluorodeoxyglucose positronemission tomography/computed tomography imaging
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996766/
https://www.ncbi.nlm.nih.gov/pubmed/24761068
http://dx.doi.org/10.4103/0972-3919.130303
work_keys_str_mv AT kamaleshwarankoramadaikaruppusamy rarecaseoftrilateralretinoblastomawithspinalcanaldropmetastasisdetectedwithfluorine18fluorodeoxyglucosepositronemissiontomographycomputedtomographyimaging
AT shibudeepuk rarecaseoftrilateralretinoblastomawithspinalcanaldropmetastasisdetectedwithfluorine18fluorodeoxyglucosepositronemissiontomographycomputedtomographyimaging
AT mohananvyshakh rarecaseoftrilateralretinoblastomawithspinalcanaldropmetastasisdetectedwithfluorine18fluorodeoxyglucosepositronemissiontomographycomputedtomographyimaging
AT shintoajitsugunan rarecaseoftrilateralretinoblastomawithspinalcanaldropmetastasisdetectedwithfluorine18fluorodeoxyglucosepositronemissiontomographycomputedtomographyimaging