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Phagocytic receptors activate and immune inhibitory receptor SIRPα inhibits phagocytosis through paxillin and cofilin
The innate immune function of phagocytosis of apoptotic cells, tissue debris, pathogens, and cancer cells is essential for homeostasis, tissue repair, fighting infection, and combating malignancy. Phagocytosis is carried out in the central nervous system (CNS) by resident microglia and in both CNS a...
Autores principales: | Gitik, Miri, Kleinhaus, Rachel, Hadas, Smadar, Reichert, Fanny, Rotshenker, Shlomo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997012/ https://www.ncbi.nlm.nih.gov/pubmed/24795566 http://dx.doi.org/10.3389/fncel.2014.00104 |
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