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Impaired relaxation despite upregulated calcium-handling protein atrial myocardium from type 2 diabetic patients with preserved ejection fraction

BACKGROUND: Diastolic dysfunction is a key factor in the development and pathology of cardiac dysfunction in diabetes, however the exact underlying mechanism remains unknown, especially in humans. We aimed to measure contraction, relaxation, expression of calcium-handling proteins and fibrosis in my...

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Detalles Bibliográficos
Autores principales:	Lamberts, Regis R, Lingam, Shivanjali J, Wang, Heng-Yu, Bollen, Ilse AE, Hughes, Gillian, Galvin, Ivor F, Bunton, Richard W, Bahn, Andrew, Katare, Rajesh, Baldi, J Chris, Williams, Michael JA, Saxena, Pankaj, Coffey, Sean, Jones, Peter P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997226/ https://www.ncbi.nlm.nih.gov/pubmed/24708792 http://dx.doi.org/10.1186/1475-2840-13-72

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