Quantitative-Proteomic Comparison of Alpha and Beta Cells to Uncover Novel Targets for Lineage Reprogramming

Type-1 diabetes (T1D) is an autoimmune disease in which insulin-secreting pancreatic beta cells are destroyed by the immune system. An emerging strategy to regenerate beta-cell mass is through transdifferentiation of pancreatic alpha cells to beta cells. We previously reported two small molecules, B...

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Detalles Bibliográficos
Autores principales: Choudhary, Amit, Hu He, Kaihui, Mertins, Philipp, Udeshi, Namrata D., Dančík, Vlado, Fomina-Yadlin, Dina, Kubicek, Stefan, Clemons, Paul A., Schreiber, Stuart L., Carr, Steven A., Wagner, Bridget K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997365/
https://www.ncbi.nlm.nih.gov/pubmed/24759943
http://dx.doi.org/10.1371/journal.pone.0095194

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