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Brd4 Is Essential for IL-1β-Induced Inflammation in Human Airway Epithelial Cells

BACKGROUND: Chronic inflammation and oxidative stress are key features of chronic obstructive pulmonary disease (COPD). Oxidative stress enhances COPD inflammation under the control of the pro-inflammatory redox-sensitive transcription factor nuclear factor-kappaB (NF-κB). Histone acetylation plays...

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Detalles Bibliográficos
Autores principales: Khan, Younis M., Kirkham, Paul, Barnes, Peter J., Adcock, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997389/
https://www.ncbi.nlm.nih.gov/pubmed/24759736
http://dx.doi.org/10.1371/journal.pone.0095051