Cargando…
Influenza viral vectors expressing the Brucella OMP16 or L7/L12 proteins as vaccines against B. abortus infection
BACKGROUND: We generated novel, effective candidate vaccine against Brucella abortus based on recombinant influenza viruses expressing the Brucella ribosomal protein L7/L12 or outer membrane protein (Omp)-16 from the NS1 open reading frame. The main purpose of this work was to evaluate the safety, i...
Autores principales: | Tabynov, Kaissar, Sansyzbay, Abylai, Kydyrbayev, Zhailaubay, Yespembetov, Bolat, Ryskeldinova, Sholpan, Zinina, Nadezhda, Assanzhanova, Nurika, Sultankulova, Kulaisan, Sandybayev, Nurlan, Khairullin, Berik, Kuznetsova, Irina, Ferko, Boris, Egorov, Andrej |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997475/ https://www.ncbi.nlm.nih.gov/pubmed/24716528 http://dx.doi.org/10.1186/1743-422X-11-69 |
Ejemplares similares
-
A new candidate vaccine for human brucellosis based on influenza viral vectors: a preliminary investigation for the development of an immunization schedule in a guinea pig model
por: Bugybayeva, Dina, et al.
Publicado: (2021) -
Development of Human Vectored Brucellosis Vaccine Formulation: Assessment of Safety and Protectiveness of Influenza Viral Vectors Expressing Brucella Immunodominant Proteins in Mice and Guinea Pigs
por: Bugybayeva, Dina, et al.
Publicado: (2020) -
Registered Influenza Viral Vector Based Brucella abortus Vaccine for Cattle in Kazakhstan: Age-Wise Safety and Efficacy Studies
por: Ryskeldinova, Sholpan, et al.
Publicado: (2021) -
Improved influenza viral vector based Brucella abortus vaccine induces robust B and T-cell responses and protection against Brucella melitensis infection in pregnant sheep and goats
por: Mailybayeva, Aigerim, et al.
Publicado: (2017) -
Evaluation of Duration of Immunogenicity and Protective Efficacy of Improved Influenza Viral Vector–Based Brucella abortus Vaccine Against Brucella melitensis Infection in Sheep and Goats
por: Mailybayeva, Aigerim, et al.
Publicado: (2020)