Aminostyrylbenzofuran Directly Reduces Oligomeric Amyloid-β and Reverses Cognitive Deficits in Alzheimer Transgenic Mice

Alzheimer's disease is an irreversible neurodegenerative disorder that is characterized by the abnormal aggregation of amyloid-β into neurotoxic oligomers and plaques. Although many disease-modifying molecules are currently in Alzheimer clinical trials, a small molecule that inhibits amyloid-β...

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Detalles Bibliográficos
Autores principales: Lee, Sang-Hyun, Kim, YoungSoo, Kim, Hye Yun, Kim, Young Hoon, Kim, Maeng Sup, Kong, Jae Yang, Lee, Mun-Han, Kim, Dong Jin, Ahn, Young Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997483/
https://www.ncbi.nlm.nih.gov/pubmed/24760018
http://dx.doi.org/10.1371/journal.pone.0095733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997483/
https://www.ncbi.nlm.nih.gov/pubmed/24760018
http://dx.doi.org/10.1371/journal.pone.0095733

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