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Aminostyrylbenzofuran Directly Reduces Oligomeric Amyloid-β and Reverses Cognitive Deficits in Alzheimer Transgenic Mice
Alzheimer's disease is an irreversible neurodegenerative disorder that is characterized by the abnormal aggregation of amyloid-β into neurotoxic oligomers and plaques. Although many disease-modifying molecules are currently in Alzheimer clinical trials, a small molecule that inhibits amyloid-β...
Autores principales: | Lee, Sang-Hyun, Kim, YoungSoo, Kim, Hye Yun, Kim, Young Hoon, Kim, Maeng Sup, Kong, Jae Yang, Lee, Mun-Han, Kim, Dong Jin, Ahn, Young Gil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997483/ https://www.ncbi.nlm.nih.gov/pubmed/24760018 http://dx.doi.org/10.1371/journal.pone.0095733 |
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