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Effects of siRNA on RET/PTC3 Junction Oncogene in Papillary Thyroid Carcinoma: From Molecular and Cellular Studies to Preclinical Investigations

RET/PTC3 junction oncogene is typical of radiation-induced childhood papillary thyroid carcinoma (PTC) with a short latency period. Since, RET/PTC3 is only present in the tumour cells, thus represents an interesting target for specific therapy by small interfering RNA (siRNA). Our aim is to demonstr...

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Detalles Bibliográficos
Autores principales: Ali, Hafiz Muhammad, Urbinati, Giorgia, Chapuis, Hubert, DesmaEle, Didier, Bertrand, Jean-Rémi, Couvreur, Patrick, Massaad-Massade, Liliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997558/
https://www.ncbi.nlm.nih.gov/pubmed/24759995
http://dx.doi.org/10.1371/journal.pone.0095964