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Autophagy: A novel therapeutic target for hepatocarcinoma (Review)

Autophagy is a highly conserved intracellular degradation process and plays an important role in hepatocarcinogenesis. Available data show that autophagy is involved in anti-hepatocarcinoma (HCC) therapies. Autophagy regulation involves a novel target for overcoming therapeutic resistance and sensit...

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Detalles Bibliográficos
Autores principales: WANG, ZHANGGUI, HAN, WEIDONG, SUI, XINBING, FANG, YONG, PAN, HONGMING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997714/
https://www.ncbi.nlm.nih.gov/pubmed/24765136
http://dx.doi.org/10.3892/ol.2014.1916
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author WANG, ZHANGGUI
HAN, WEIDONG
SUI, XINBING
FANG, YONG
PAN, HONGMING
author_facet WANG, ZHANGGUI
HAN, WEIDONG
SUI, XINBING
FANG, YONG
PAN, HONGMING
author_sort WANG, ZHANGGUI
collection PubMed
description Autophagy is a highly conserved intracellular degradation process and plays an important role in hepatocarcinogenesis. Available data show that autophagy is involved in anti-hepatocarcinoma (HCC) therapies. Autophagy regulation involves a novel target for overcoming therapeutic resistance and sensitizing HCC to currently therapeutic methods. This is a systematic review on the interface of autophagy and the development of HCC and outlining the role of autophagy in current anti-HCC approaches. Understanding the significance of autophagy in anti-HCC therapy may offer a novel therapeutic target for improving anti-cancer efficacy and prolong survival for HCC patients.
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spelling pubmed-39977142014-04-24 Autophagy: A novel therapeutic target for hepatocarcinoma (Review) WANG, ZHANGGUI HAN, WEIDONG SUI, XINBING FANG, YONG PAN, HONGMING Oncol Lett Articles Autophagy is a highly conserved intracellular degradation process and plays an important role in hepatocarcinogenesis. Available data show that autophagy is involved in anti-hepatocarcinoma (HCC) therapies. Autophagy regulation involves a novel target for overcoming therapeutic resistance and sensitizing HCC to currently therapeutic methods. This is a systematic review on the interface of autophagy and the development of HCC and outlining the role of autophagy in current anti-HCC approaches. Understanding the significance of autophagy in anti-HCC therapy may offer a novel therapeutic target for improving anti-cancer efficacy and prolong survival for HCC patients. D.A. Spandidos 2014-05 2014-02-26 /pmc/articles/PMC3997714/ /pubmed/24765136 http://dx.doi.org/10.3892/ol.2014.1916 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
WANG, ZHANGGUI
HAN, WEIDONG
SUI, XINBING
FANG, YONG
PAN, HONGMING
Autophagy: A novel therapeutic target for hepatocarcinoma (Review)
title Autophagy: A novel therapeutic target for hepatocarcinoma (Review)
title_full Autophagy: A novel therapeutic target for hepatocarcinoma (Review)
title_fullStr Autophagy: A novel therapeutic target for hepatocarcinoma (Review)
title_full_unstemmed Autophagy: A novel therapeutic target for hepatocarcinoma (Review)
title_short Autophagy: A novel therapeutic target for hepatocarcinoma (Review)
title_sort autophagy: a novel therapeutic target for hepatocarcinoma (review)
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997714/
https://www.ncbi.nlm.nih.gov/pubmed/24765136
http://dx.doi.org/10.3892/ol.2014.1916
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