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Adenoid cystic carcinoma of the breast: A case report and literature review

Adenoid cystic carcinoma (ACC) is a rare malignant tumor of the breast that occurs in <0.1% of all patients diagnosed with breast cancer. The mean patient age at the time of diagnosis is 50–60 years. Typically, the tumor presents as a subareolar mass or as pain in the breast. While the radiologic...

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Autores principales: CANYILMAZ, EMINE, USLU, GONCA HANEDAN, MEMİŞ, YAHYAHAN, BAHAT, ZÜMRÜT, YILDIZ, KADRIYE, YONEY, ADNAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997715/
https://www.ncbi.nlm.nih.gov/pubmed/24765184
http://dx.doi.org/10.3892/ol.2014.1945
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author CANYILMAZ, EMINE
USLU, GONCA HANEDAN
MEMİŞ, YAHYAHAN
BAHAT, ZÜMRÜT
YILDIZ, KADRIYE
YONEY, ADNAN
author_facet CANYILMAZ, EMINE
USLU, GONCA HANEDAN
MEMİŞ, YAHYAHAN
BAHAT, ZÜMRÜT
YILDIZ, KADRIYE
YONEY, ADNAN
author_sort CANYILMAZ, EMINE
collection PubMed
description Adenoid cystic carcinoma (ACC) is a rare malignant tumor of the breast that occurs in <0.1% of all patients diagnosed with breast cancer. The mean patient age at the time of diagnosis is 50–60 years. Typically, the tumor presents as a subareolar mass or as pain in the breast. While the radiological appearances of ACC are generally non-specific, the diagnosis can be made on fine-needle aspiration cytology. In the present study, a 58-year-old female patient was admitted to the Department of Radiation Oncology (Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey) with complaints of pain in the upper outer quadrant of the right breast. An excision biopsy of a lump in the upper outer quadrant revealed ACC, and perineural invasion was present. Subsequently, the patient underwent breast conservation surgery and sentinel lymph node dissection. Pathology from the second surgery depicted ACC in the form of microscopic foci around the initial surgical cavity, with two reactive sentinel lymph nodes and the closest negative margin at 2 mm. The patient was treated with radiotherapy following the surgery. No recurrence and metastasis were found after 20 months of follow-up. In conclusion, mammary ACC is a rare malignant neoplasm of the breast. Although surgery is the main treatment, the optimal adjuvant treatment of ACC of the breast has not yet been determined due to its low incidence.
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spelling pubmed-39977152014-04-24 Adenoid cystic carcinoma of the breast: A case report and literature review CANYILMAZ, EMINE USLU, GONCA HANEDAN MEMİŞ, YAHYAHAN BAHAT, ZÜMRÜT YILDIZ, KADRIYE YONEY, ADNAN Oncol Lett Articles Adenoid cystic carcinoma (ACC) is a rare malignant tumor of the breast that occurs in <0.1% of all patients diagnosed with breast cancer. The mean patient age at the time of diagnosis is 50–60 years. Typically, the tumor presents as a subareolar mass or as pain in the breast. While the radiological appearances of ACC are generally non-specific, the diagnosis can be made on fine-needle aspiration cytology. In the present study, a 58-year-old female patient was admitted to the Department of Radiation Oncology (Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey) with complaints of pain in the upper outer quadrant of the right breast. An excision biopsy of a lump in the upper outer quadrant revealed ACC, and perineural invasion was present. Subsequently, the patient underwent breast conservation surgery and sentinel lymph node dissection. Pathology from the second surgery depicted ACC in the form of microscopic foci around the initial surgical cavity, with two reactive sentinel lymph nodes and the closest negative margin at 2 mm. The patient was treated with radiotherapy following the surgery. No recurrence and metastasis were found after 20 months of follow-up. In conclusion, mammary ACC is a rare malignant neoplasm of the breast. Although surgery is the main treatment, the optimal adjuvant treatment of ACC of the breast has not yet been determined due to its low incidence. D.A. Spandidos 2014-05 2014-03-06 /pmc/articles/PMC3997715/ /pubmed/24765184 http://dx.doi.org/10.3892/ol.2014.1945 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
CANYILMAZ, EMINE
USLU, GONCA HANEDAN
MEMİŞ, YAHYAHAN
BAHAT, ZÜMRÜT
YILDIZ, KADRIYE
YONEY, ADNAN
Adenoid cystic carcinoma of the breast: A case report and literature review
title Adenoid cystic carcinoma of the breast: A case report and literature review
title_full Adenoid cystic carcinoma of the breast: A case report and literature review
title_fullStr Adenoid cystic carcinoma of the breast: A case report and literature review
title_full_unstemmed Adenoid cystic carcinoma of the breast: A case report and literature review
title_short Adenoid cystic carcinoma of the breast: A case report and literature review
title_sort adenoid cystic carcinoma of the breast: a case report and literature review
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997715/
https://www.ncbi.nlm.nih.gov/pubmed/24765184
http://dx.doi.org/10.3892/ol.2014.1945
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