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Molecular characterization of Plasmodium falciparum uracil-DNA glycosylase and its potential as a new anti-malarial drug target
BACKGROUND: Based on resistance of currently used anti-malarials, a new anti-malarial drug target against Plasmodium falciparum is urgently needed. Damaged DNA cannot be transcribed without prior DNA repair; therefore, uracil-DNA glycosylase, playing an important role in base excision repair, may ac...
Autores principales: | Suksangpleng, Thidarat, Leartsakulpanich, Ubolsree, Moonsom, Saengduen, Siribal, Saranya, Boonyuen, Usa, Wright, George E, Chavalitshewinkoon-Petmitr, Porntip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997752/ https://www.ncbi.nlm.nih.gov/pubmed/24742318 http://dx.doi.org/10.1186/1475-2875-13-149 |
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