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Phenotype and regulation of immunosuppressive Vδ2-expressing γδ T cells
The proliferation and interleukin-2 production of CD4(+)CD25(−) αβ T cells were inhibited in a cell-contact manner by Vδ2 γδ T cells. The transcription factor Helios was constitutively expressed in about one-third of circulating γδ T cells and was upregulated by CD28-signaling. Our data suggest that...
Autores principales: | Peters, Christian, Oberg, Hans-Heinrich, Kabelitz, Dieter, Wesch, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Basel
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997799/ https://www.ncbi.nlm.nih.gov/pubmed/24091816 http://dx.doi.org/10.1007/s00018-013-1467-1 |
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