Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis

OBJECTIVES: Relaxation of vascular smooth muscle (VSM) requires re-uptake of cytosolic Ca(2+) into the sarcoplasmic reticulum (SR) via the Sarco/Endoplasmic Reticulum Ca(2+) ATPase (SERCA), or extrusion via the Plasma Membrane Ca(2+) ATPase (PMCA) or sodium Ca(2+) exchanger (NCX). Peroxynitrite, a r...

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Detalles Bibliográficos
Autores principales: Ewart, Marie-Ann, Kennedy, Simon, MacMillan, Debbi, Raja, Abhirami L.N., Watt, Ian M., Currie, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997800/
https://www.ncbi.nlm.nih.gov/pubmed/24657385
http://dx.doi.org/10.1016/j.atherosclerosis.2014.02.014

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