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Transcriptomic changes in the frontal cortex associated with paternal age
BACKGROUND: Advanced paternal age is robustly associated with several human neuropsychiatric disorders, particularly autism. The precise mechanism(s) mediating the paternal age effect are not known, but they are thought to involve the accumulation of de novo (epi)genomic alterations. In this study w...
Autores principales: | Smith, Rebecca G, Fernandes, Cathy, Kember, Rachel, Schalkwyk, Leonard C, Buxbaum, Joseph, Reichenberg, Abraham, Mill, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998024/ https://www.ncbi.nlm.nih.gov/pubmed/24655730 http://dx.doi.org/10.1186/2040-2392-5-24 |
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