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Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics
Multispectral imaging is a highly desirable modality for material-based analysis in diverse areas such as food production and processing, satellite-based reconnaissance, and biomedical imaging. Here, we present nanofilter-based multispectral videography (nMSV) in the 700 to 950 nm range made possibl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998030/ https://www.ncbi.nlm.nih.gov/pubmed/24759647 http://dx.doi.org/10.1038/srep04737 |
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author | Najiminaini, Mohamadreza Kaminska, Bozena St. Lawrence, Keith Carson, Jeffrey J. L. |
author_facet | Najiminaini, Mohamadreza Kaminska, Bozena St. Lawrence, Keith Carson, Jeffrey J. L. |
author_sort | Najiminaini, Mohamadreza |
collection | PubMed |
description | Multispectral imaging is a highly desirable modality for material-based analysis in diverse areas such as food production and processing, satellite-based reconnaissance, and biomedical imaging. Here, we present nanofilter-based multispectral videography (nMSV) in the 700 to 950 nm range made possible by the tunable extraordinary-optical-transmission properties of 3D metallic nanostructures. Measurements made with nMSV during a bolus injection of an intravascular tracer in the ear of a piglet resulted in spectral videos of the microvasculature. Analysis of the multispectral videos generated contrast measurements representative of arterial pulsation, the distribution of microvascular transit times, as well as a separation of the venous and arterial signals arising from within the tissue. Therefore, nMSV is capable of acquiring serial multispectral images relevant to tissue hemodynamics, which may have application to the detection and identification of skin cancer. |
format | Online Article Text |
id | pubmed-3998030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-39980302014-04-24 Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics Najiminaini, Mohamadreza Kaminska, Bozena St. Lawrence, Keith Carson, Jeffrey J. L. Sci Rep Article Multispectral imaging is a highly desirable modality for material-based analysis in diverse areas such as food production and processing, satellite-based reconnaissance, and biomedical imaging. Here, we present nanofilter-based multispectral videography (nMSV) in the 700 to 950 nm range made possible by the tunable extraordinary-optical-transmission properties of 3D metallic nanostructures. Measurements made with nMSV during a bolus injection of an intravascular tracer in the ear of a piglet resulted in spectral videos of the microvasculature. Analysis of the multispectral videos generated contrast measurements representative of arterial pulsation, the distribution of microvascular transit times, as well as a separation of the venous and arterial signals arising from within the tissue. Therefore, nMSV is capable of acquiring serial multispectral images relevant to tissue hemodynamics, which may have application to the detection and identification of skin cancer. Nature Publishing Group 2014-04-24 /pmc/articles/PMC3998030/ /pubmed/24759647 http://dx.doi.org/10.1038/srep04737 Text en Copyright © 2014, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images in this article are included in the article's Creative Commons license, unless indicated otherwise in the image credit; if the image is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the image. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/ |
spellingShingle | Article Najiminaini, Mohamadreza Kaminska, Bozena St. Lawrence, Keith Carson, Jeffrey J. L. Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics |
title | Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics |
title_full | Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics |
title_fullStr | Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics |
title_full_unstemmed | Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics |
title_short | Bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics |
title_sort | bolus tracking with nanofilter-based multispectral videography for capturing microvasculature hemodynamics |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998030/ https://www.ncbi.nlm.nih.gov/pubmed/24759647 http://dx.doi.org/10.1038/srep04737 |
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