Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin)

BACKGROUND: Macroautophagy is a catabolic process that can mediate cell death or survival. Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) treatment (TR) is known to induce autophagy. Here we investigated whether SQSTM1/p62 (p62) overexpression, as a marker of aut...

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Detalles Bibliográficos
Autores principales: Singh, Kamini, Sharma, Arishya, Mir, Maria C, Drazba, Judith A, Heston, Warren D, Magi-Galluzzi, Cristina, Hansel, Donna, Rubin, Brian P, Klein, Eric A, Almasan, Alexandru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998041/
https://www.ncbi.nlm.nih.gov/pubmed/24655592
http://dx.doi.org/10.1186/1476-4598-13-70

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