Increased protein aggregation in Zucker Diabetic Fatty rat brain: identification of key mechanistic targets and the therapeutic application of hydrogen sulfide

BACKGROUND: Diabetes and particularly high blood glucose levels are implicated in neurodegeneration. One of the hallmarks of neurodegeneration is protein aggregation. We investigated the presence of protein aggregation in the frontal brain of Zucker diabetic fatty (ZDF) rats, an animal model for dia...

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Detalles Bibliográficos
Autores principales: Talaei, Fatemeh, Van Praag, Veroniek M, Shishavan, Mahdi H, Landheer, Sjoerd W, Buikema, Henk, Henning, Robert H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998068/
https://www.ncbi.nlm.nih.gov/pubmed/24393531
http://dx.doi.org/10.1186/1471-2121-15-1

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