Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency

Mammalian somatic cells can be directly reprogrammed into induced pluripotent stem cells (iPSCs) by introducing defined sets of transcription factors. Somatic cell reprogramming involves epigenomic reconfiguration, conferring iPSCs with characteristics similar to embryonic stem cells (ESCs). Human E...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Wu, Hao, Li, Yujing, Szulwach, Keith E., Lin, Li, Li, Xuekun, Chen, I-Ping, Goldlust, Ian S., Chamberlain, Stormy J., Dodd, Ann, Gong, He, Ananiev, Gene, Han, Ji Woong, Yoon, Young-sup, Rudd, M. Katharine, Yu, Miao, Song, Chun-Xiao, He, Chuan, Chang, Qiang, Warren, Stephen T., Jin, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998089/
https://www.ncbi.nlm.nih.gov/pubmed/23685628
http://dx.doi.org/10.1038/ncb2748

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