Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

BACKGROUND: Constitutive activation of signal transducer and activator of transcription 3 (STAT3) has been linked with proliferation, survival, invasion and angiogenesis of a variety of human cancer cells, including hepatocellular carcinoma (HCC). Thus, novel agents that can suppress STAT3 activatio...

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Detalles Bibliográficos
Autores principales: Sethi, Gautam, Chatterjee, Snehajyoti, Rajendran, Peramaiyan, Li, Feng, Shanmugam, Muthu K, Wong, Kwong Fai, Kumar, Alan Prem, Senapati, Parijat, Behera, Amit K, Hui, Kam Man, Basha, Jeelan, Natesh, Nagashayana, Luk, John M, Kundu, Tapas K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998115/
https://www.ncbi.nlm.nih.gov/pubmed/24655440
http://dx.doi.org/10.1186/1476-4598-13-66

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