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jmodeltest.org: selection of nucleotide substitution models on the cloud

Summary: The selection of models of nucleotide substitution is one of the major steps of modern phylogenetic analysis. Different tools exist to accomplish this task, among which jModelTest 2 (jMT2) is one of the most popular. Still, to deal with large DNA alignments with hundreds or thousands of loc...

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Detalles Bibliográficos
Autores principales: Santorum, Jose Manuel, Darriba, Diego, Taboada, Guillermo L., Posada, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998143/
https://www.ncbi.nlm.nih.gov/pubmed/24451621
http://dx.doi.org/10.1093/bioinformatics/btu032
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author Santorum, Jose Manuel
Darriba, Diego
Taboada, Guillermo L.
Posada, David
author_facet Santorum, Jose Manuel
Darriba, Diego
Taboada, Guillermo L.
Posada, David
author_sort Santorum, Jose Manuel
collection PubMed
description Summary: The selection of models of nucleotide substitution is one of the major steps of modern phylogenetic analysis. Different tools exist to accomplish this task, among which jModelTest 2 (jMT2) is one of the most popular. Still, to deal with large DNA alignments with hundreds or thousands of loci, users of jMT2 need to have access to High Performance Computing clusters, including installation and configuration capabilities, conditions not always met. Here we present jmodeltest.org, a novel web server for the transparent execution of jMT2 across different platforms and for a wide range of users. Its main benefit is straightforward execution, avoiding any configuration/execution issues, and reducing significantly in most cases the time required to complete the analysis. Availability and implementation: jmodeltest.org is accessible using modern browsers, such as Firefox, Chrome, Opera, Safari and IE from http://jmodeltest.org. User registration is not mandatory, but users wanting to have additional functionalities, like access to previous analyses, have the possibility of opening a user account. Contact: info@jmodeltest.org
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spelling pubmed-39981432014-04-24 jmodeltest.org: selection of nucleotide substitution models on the cloud Santorum, Jose Manuel Darriba, Diego Taboada, Guillermo L. Posada, David Bioinformatics Applications Notes Summary: The selection of models of nucleotide substitution is one of the major steps of modern phylogenetic analysis. Different tools exist to accomplish this task, among which jModelTest 2 (jMT2) is one of the most popular. Still, to deal with large DNA alignments with hundreds or thousands of loci, users of jMT2 need to have access to High Performance Computing clusters, including installation and configuration capabilities, conditions not always met. Here we present jmodeltest.org, a novel web server for the transparent execution of jMT2 across different platforms and for a wide range of users. Its main benefit is straightforward execution, avoiding any configuration/execution issues, and reducing significantly in most cases the time required to complete the analysis. Availability and implementation: jmodeltest.org is accessible using modern browsers, such as Firefox, Chrome, Opera, Safari and IE from http://jmodeltest.org. User registration is not mandatory, but users wanting to have additional functionalities, like access to previous analyses, have the possibility of opening a user account. Contact: info@jmodeltest.org Oxford University Press 2014-05-01 2014-01-21 /pmc/articles/PMC3998143/ /pubmed/24451621 http://dx.doi.org/10.1093/bioinformatics/btu032 Text en © The Author 2014. Published by Oxford University Press. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Santorum, Jose Manuel
Darriba, Diego
Taboada, Guillermo L.
Posada, David
jmodeltest.org: selection of nucleotide substitution models on the cloud
title jmodeltest.org: selection of nucleotide substitution models on the cloud
title_full jmodeltest.org: selection of nucleotide substitution models on the cloud
title_fullStr jmodeltest.org: selection of nucleotide substitution models on the cloud
title_full_unstemmed jmodeltest.org: selection of nucleotide substitution models on the cloud
title_short jmodeltest.org: selection of nucleotide substitution models on the cloud
title_sort jmodeltest.org: selection of nucleotide substitution models on the cloud
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998143/
https://www.ncbi.nlm.nih.gov/pubmed/24451621
http://dx.doi.org/10.1093/bioinformatics/btu032
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