2-[2-(4-Methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione

In the title compound, C(15)H(19)N(3)O(2), the piperazine ring adopts a chair conformation, with its N—C bonds in pseudo-equatorial orientations. The dihedral angle between the C atoms of the piperazine ring and the phthalamide ring system (r.m.s. deviaiton = 0.008 Å) is 89.30 (8)°. In the crystal,...

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Detalles Bibliográficos
Autores principales: Zhou, Mi, Shao, Ying, Xia, Yong-an, Liu, Xiao-Long, Sun, Xiao-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998427/
https://www.ncbi.nlm.nih.gov/pubmed/24764996
http://dx.doi.org/10.1107/S1600536814002232
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author Zhou, Mi
Shao, Ying
Xia, Yong-an
Liu, Xiao-Long
Sun, Xiao-Qiang
author_facet Zhou, Mi
Shao, Ying
Xia, Yong-an
Liu, Xiao-Long
Sun, Xiao-Qiang
author_sort Zhou, Mi
collection PubMed
description In the title compound, C(15)H(19)N(3)O(2), the piperazine ring adopts a chair conformation, with its N—C bonds in pseudo-equatorial orientations. The dihedral angle between the C atoms of the piperazine ring and the phthalamide ring system (r.m.s. deviaiton = 0.008 Å) is 89.30 (8)°. In the crystal, mol­ecules are linked by C—H⋯O hydrogen bonds, generating a three-dimensional network and aromatic π–π inter­actions also occur [centroid–centroid distances = 3.556 (1)–3.716 (1) Å].
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spelling pubmed-39984272014-04-24 2-[2-(4-Methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione Zhou, Mi Shao, Ying Xia, Yong-an Liu, Xiao-Long Sun, Xiao-Qiang Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(15)H(19)N(3)O(2), the piperazine ring adopts a chair conformation, with its N—C bonds in pseudo-equatorial orientations. The dihedral angle between the C atoms of the piperazine ring and the phthalamide ring system (r.m.s. deviaiton = 0.008 Å) is 89.30 (8)°. In the crystal, mol­ecules are linked by C—H⋯O hydrogen bonds, generating a three-dimensional network and aromatic π–π inter­actions also occur [centroid–centroid distances = 3.556 (1)–3.716 (1) Å]. International Union of Crystallography 2014-02-12 /pmc/articles/PMC3998427/ /pubmed/24764996 http://dx.doi.org/10.1107/S1600536814002232 Text en © Zhou et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhou, Mi
Shao, Ying
Xia, Yong-an
Liu, Xiao-Long
Sun, Xiao-Qiang
2-[2-(4-Methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione
title 2-[2-(4-Methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione
title_full 2-[2-(4-Methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione
title_fullStr 2-[2-(4-Methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione
title_full_unstemmed 2-[2-(4-Methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione
title_short 2-[2-(4-Methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione
title_sort 2-[2-(4-methyl­piperazin-1-yl)eth­yl]iso­indoline-1,3-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998427/
https://www.ncbi.nlm.nih.gov/pubmed/24764996
http://dx.doi.org/10.1107/S1600536814002232
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