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Methyl 4′-(3-bromo­phen­yl)-3′-(2,5-di­methyl­benz­yl)-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate

In the title compound, C(29)H(29)BrN(2)O(3), the indole ring system is essentially planar (r.m.s. deviation = 0.079 Å) and makes a dihedral angle of 85.23 (10)° with the mean plane of the 4-methyl­pyrrolidine ring. This ring adopts an envelope conformation with the N atom at the flap. The pyrrolidin...

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Detalles Bibliográficos
Autores principales: Karthikeyan, S., Sethusankar, K., Devaraj, Anthonisamy, Bakthadoss, Manickam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998460/
https://www.ncbi.nlm.nih.gov/pubmed/24765004
http://dx.doi.org/10.1107/S1600536814002967
Descripción
Sumario:In the title compound, C(29)H(29)BrN(2)O(3), the indole ring system is essentially planar (r.m.s. deviation = 0.079 Å) and makes a dihedral angle of 85.23 (10)° with the mean plane of the 4-methyl­pyrrolidine ring. This ring adopts an envelope conformation with the N atom at the flap. The pyrrolidine ring of the indole ring system adopts a twisted conformation on the C—C(=O) bond. The mol­ecular structure is stabilized by an intra­molecular C—H⋯O hydrogen bond, which generates an S(6) ring motif. In the crystal, mol­ecules are linked via pairs of C—H⋯O hydrogen bonds, forming inversion dimers with an R (2) (2)(14) ring motif. These dimers are further linked by N—H⋯O and C—H⋯O hydrogen bonds, forming two-dimensional networks lying parallel to (10-1).