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N-(5-Benzylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(piperidin-1-yl)acetamide
The title compound, C(16)H(20)N(4)OS(2), was synthesized by the reaction of 2-benzylsulfanyl-5-chloroacetamido-1,3,4-thiadiazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thiadiazole units are twisted by 10.8 (4)°. The thiadiazole S atom and the acetamide O atom are s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998473/ https://www.ncbi.nlm.nih.gov/pubmed/24764962 http://dx.doi.org/10.1107/S160053681400213X |
| Sumario: | The title compound, C(16)H(20)N(4)OS(2), was synthesized by the reaction of 2-benzylsulfanyl-5-chloroacetamido-1,3,4-thiadiazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thiadiazole units are twisted by 10.8 (4)°. The thiadiazole S atom and the acetamide O atom are syn-oriented due to a hypervalent S⋯O interaction of 2.628 (4) Å. In the crystal, molecules form centrosymmetric dimers via N—H⋯N hydrogen bonds. These dimers are further connected by C—H⋯O interactions into (100) layers. |
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