N-(5-Benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide

The title compound, C(16)H(20)N(4)OS(2), was synthesized by the reaction of 2-benzyl­sulfanyl-5-chloro­acetamido-1,3,4-thia­diazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thia­diazole units are twisted by 10.8 (4)°. The thia­diazole S atom and the acetamide O atom are s...

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Detalles Bibliográficos
Autores principales: Ismailova, D. S., Okmanov, R. Ya., Ziyaev, A. A., Shakhidoyatov, Kh. M., Tashkhodjaev, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998473/
https://www.ncbi.nlm.nih.gov/pubmed/24764962
http://dx.doi.org/10.1107/S160053681400213X
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author Ismailova, D. S.
Okmanov, R. Ya.
Ziyaev, A. A.
Shakhidoyatov, Kh. M.
Tashkhodjaev, B.
author_facet Ismailova, D. S.
Okmanov, R. Ya.
Ziyaev, A. A.
Shakhidoyatov, Kh. M.
Tashkhodjaev, B.
author_sort Ismailova, D. S.
collection PubMed
description The title compound, C(16)H(20)N(4)OS(2), was synthesized by the reaction of 2-benzyl­sulfanyl-5-chloro­acetamido-1,3,4-thia­diazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thia­diazole units are twisted by 10.8 (4)°. The thia­diazole S atom and the acetamide O atom are syn-oriented due to a hypervalent S⋯O inter­action of 2.628 (4) Å. In the crystal, mol­ecules form centrosymmetric dimers via N—H⋯N hydrogen bonds. These dimers are further connected by C—H⋯O inter­actions into (100) layers.
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spelling pubmed-39984732014-04-24 N-(5-Benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide Ismailova, D. S. Okmanov, R. Ya. Ziyaev, A. A. Shakhidoyatov, Kh. M. Tashkhodjaev, B. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(16)H(20)N(4)OS(2), was synthesized by the reaction of 2-benzyl­sulfanyl-5-chloro­acetamido-1,3,4-thia­diazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thia­diazole units are twisted by 10.8 (4)°. The thia­diazole S atom and the acetamide O atom are syn-oriented due to a hypervalent S⋯O inter­action of 2.628 (4) Å. In the crystal, mol­ecules form centrosymmetric dimers via N—H⋯N hydrogen bonds. These dimers are further connected by C—H⋯O inter­actions into (100) layers. International Union of Crystallography 2014-02-05 /pmc/articles/PMC3998473/ /pubmed/24764962 http://dx.doi.org/10.1107/S160053681400213X Text en © Ismailova et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ismailova, D. S.
Okmanov, R. Ya.
Ziyaev, A. A.
Shakhidoyatov, Kh. M.
Tashkhodjaev, B.
N-(5-Benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide
title N-(5-Benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide
title_full N-(5-Benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide
title_fullStr N-(5-Benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide
title_full_unstemmed N-(5-Benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide
title_short N-(5-Benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide
title_sort n-(5-benzyl­sulfanyl-1,3,4-thia­diazol-2-yl)-2-(piperidin-1-yl)acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998473/
https://www.ncbi.nlm.nih.gov/pubmed/24764962
http://dx.doi.org/10.1107/S160053681400213X
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