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5-Chloro-5′′-(4-chloro­benzyl­idene)-4′-(4-chloro­phen­yl)-1′,1′′-dimethyldi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione

The racemic title compound, C(30)H(26)Cl(3)N(3)O(2), comprises two spiro links, the first connecting the piperidine and pyrrolidine rings and the other connecting the indole and pyrrolidine rings. The piperidine ring adopts a half-chair conformation, while the pyrrolidine ring has an envelope confor...

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Detalles Bibliográficos
Autores principales: Farag, I. S. Ahmed, Girgis, Adel S., Ramadan, A. A., Moustafa, A. M., Mabied, Ahmed F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998502/
https://www.ncbi.nlm.nih.gov/pubmed/24765059
http://dx.doi.org/10.1107/S1600536814004309
Descripción
Sumario:The racemic title compound, C(30)H(26)Cl(3)N(3)O(2), comprises two spiro links, the first connecting the piperidine and pyrrolidine rings and the other connecting the indole and pyrrolidine rings. The piperidine ring adopts a half-chair conformation, while the pyrrolidine ring has an envelope conformation with the unsubstituted C atom as the flap. The dihedral angles between the two p-Cl-substituted benzene rings and the indole ring are 33.13 (14) and 54.11 (14)°. In the crystal, mol­ecules form inversion dimers through pairs of N—H⋯O hydrogen bonds [graph set R (2) (2)(8)]. Aromatic C—H⋯O hydrogen bonds extend these dimers into a ribbon structure, enclosing R (2) (2)(14) ring motifs, along the a-axis direction.