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Qualitative and Quantitative Characterization of Plasma Proteins When Incorporating Traveling Wave Ion Mobility into a Liquid Chromatography–Mass Spectrometry Workflow for Biomarker Discovery: Use of Product Ion Quantitation As an Alternative Data Analysis Tool for Label Free Quantitation

[Image: see text] Discovery of protein biomarkers in clinical samples necessitates significant prefractionation prior to liquid chromatography–mass spectrometry (LC–MS) analysis. Integrating traveling wave ion mobility spectrometry (TWIMS) enables in-line gas phase separation which when coupled with...

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Detalles Bibliográficos
Autores principales:	Daly, Charlotte E., Ng, Leong L., Hakimi, Amirmansoor, Willingale, Richard, Jones, Donald J. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998518/ https://www.ncbi.nlm.nih.gov/pubmed/24397486 http://dx.doi.org/10.1021/ac403901t

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