2-Ethyl-3-[(R)-2-phenyl­butanamido]­quinazolin-4(3H)-one monohydrate

In the title compound, C(20)H(21)N(3)O(2)·H(2)O (EQR·H(2)O), the quinazoline ring system forms dihedral angles of 53.1 (1) and 85.6 (1)° with the phenyl ring and the amide link, respectively. In the crystal, O—H⋯O hydrogen bonds link two EQR and two water mol­ecules into a centrosymmetric R (4) (4)(...

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Autores principales: El-Hiti, Gamal A., Smith, Keith, Hegazy, Amany S., Jones, D. Heulyn, Kariuki, Benson M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998561/
https://www.ncbi.nlm.nih.gov/pubmed/24826166
http://dx.doi.org/10.1107/S1600536814005996
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author El-Hiti, Gamal A.
Smith, Keith
Hegazy, Amany S.
Jones, D. Heulyn
Kariuki, Benson M.
author_facet El-Hiti, Gamal A.
Smith, Keith
Hegazy, Amany S.
Jones, D. Heulyn
Kariuki, Benson M.
author_sort El-Hiti, Gamal A.
collection PubMed
description In the title compound, C(20)H(21)N(3)O(2)·H(2)O (EQR·H(2)O), the quinazoline ring system forms dihedral angles of 53.1 (1) and 85.6 (1)° with the phenyl ring and the amide link, respectively. In the crystal, O—H⋯O hydrogen bonds link two EQR and two water mol­ecules into a centrosymmetric R (4) (4)(18) ring motif. N—H⋯O hydrogen bonds further link these hydrogen-bonded fragments into columns extending in [010].
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spelling pubmed-39985612014-05-13 2-Ethyl-3-[(R)-2-phenyl­butanamido]­quinazolin-4(3H)-one monohydrate El-Hiti, Gamal A. Smith, Keith Hegazy, Amany S. Jones, D. Heulyn Kariuki, Benson M. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(20)H(21)N(3)O(2)·H(2)O (EQR·H(2)O), the quinazoline ring system forms dihedral angles of 53.1 (1) and 85.6 (1)° with the phenyl ring and the amide link, respectively. In the crystal, O—H⋯O hydrogen bonds link two EQR and two water mol­ecules into a centrosymmetric R (4) (4)(18) ring motif. N—H⋯O hydrogen bonds further link these hydrogen-bonded fragments into columns extending in [010]. International Union of Crystallography 2014-03-22 /pmc/articles/PMC3998561/ /pubmed/24826166 http://dx.doi.org/10.1107/S1600536814005996 Text en © El-Hiti et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
El-Hiti, Gamal A.
Smith, Keith
Hegazy, Amany S.
Jones, D. Heulyn
Kariuki, Benson M.
2-Ethyl-3-[(R)-2-phenyl­butanamido]­quinazolin-4(3H)-one monohydrate
title 2-Ethyl-3-[(R)-2-phenyl­butanamido]­quinazolin-4(3H)-one monohydrate
title_full 2-Ethyl-3-[(R)-2-phenyl­butanamido]­quinazolin-4(3H)-one monohydrate
title_fullStr 2-Ethyl-3-[(R)-2-phenyl­butanamido]­quinazolin-4(3H)-one monohydrate
title_full_unstemmed 2-Ethyl-3-[(R)-2-phenyl­butanamido]­quinazolin-4(3H)-one monohydrate
title_short 2-Ethyl-3-[(R)-2-phenyl­butanamido]­quinazolin-4(3H)-one monohydrate
title_sort 2-ethyl-3-[(r)-2-phenyl­butanamido]­quinazolin-4(3h)-one monohydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998561/
https://www.ncbi.nlm.nih.gov/pubmed/24826166
http://dx.doi.org/10.1107/S1600536814005996
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